LIN7C 抗体 (AA 1-73)
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Quick Overview for LIN7C 抗体 (AA 1-73) (ABIN7869539)
抗原
See all LIN7C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-73
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原理
- Zebrafish Lin7c Antibody / Protein lin-7 homolog C
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Lin7c recombinant protein (amino acids M1-A73) was used as the immunogen for the Zebrafish Lin7c antibody.
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亚型
- Ig Fraction
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anti-Lin-7 Homolog C (LIN7C) (N-Term) antibody
LIN7C 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 168-197), (C-Term) antibodyLIN7C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32322 unconjugated
anti-Lin-7 Homolog C (LIN7C) (N-Term) antibodyLIN7C 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 108-157) antibodyLIN7C 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 1-70) antibodyLIN7C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 175-197), (C-Term) antibodyLIN7C 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Lin7c antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Lin7c antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LIN7C (Lin-7 Homolog C (LIN7C))
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别名
- Lin7c
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背景
- Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene. LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
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UniProt
- Q66IB0
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途径
- Synaptic Membrane
抗原
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