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Recombinant CD45RA 抗体 (AA 1-600)

This 兔 单克隆 antibody specifically detects CD45RA in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7869491
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD45RA 抗体 (AA 1-600) (ABIN7869491)

抗原

See all CD45RA 抗体
CD45RA

抗体类型

Recombinant Antibody

适用

  • 150
  • 9
  • 6
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  • 1

宿主

  • 139
  • 27

克隆类型

  • 165
  • 1
单克隆

标记

  • 74
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  • 2
  • 1
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  • 1
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This CD45RA antibody is un-conjugated

应用范围

  • 124
  • 55
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  • 43
  • 30
  • 17
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  • 15
  • 11
  • 4
  • 2
  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PTPRC-4367R
  • 抗原表位

    • 18
    • 4
    • 3
    AA 1-600

    原理

    CD45RA Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-600) from the human protein was used as the immunogen for the CD45RA antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the CD45RA antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CD45RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD45RA

    别名

    CD45RA

    背景

    CD45 is a family of single chain transmembrane glycoproteins, consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are rod shaped, heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1q31-32.CD45 is exclusively expressed in haematolymphoid cells. Almost all haematolymphoid cells, including precursor cells and mature B- and T-lymphocytes, granulocytes, monocytes/histiocytes and interdigitating reticulum cells and follicular dendritic cells express CD45. This protein is detected in the large majority of haematolymphoid neoplasms, i.e., leukemias and malignant lymphomas. Overall, about 90 % of malignant lymphomas are CD45 positive.CD45 is an important marker in the primary tumor screening panel in order to identify haematolymphoid differentiation. Loss of CD45 in precursor B-cell neoplasms is a negative prognostic parameter.

    UniProt

    P08575
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