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MYB 抗体 (AA 1-590)

This 兔 多克隆 antibody specifically detects MYB in WB. It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7869488
发货至: 中国
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Quick Overview for MYB 抗体 (AA 1-590) (ABIN7869488)

抗原

See all MYB 抗体
MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

适用

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斑马鱼

宿主

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克隆类型

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  • 37
多克隆

标记

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This MYB antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-590

    原理

    Zebrafish c-Myb Antibody / Myb

    纯化方法

    Antigen affinity chromatography

    免疫原

    E. coli-derived zebrafish C-myb recombinant protein (amino acids M1-I590) was used as the immunogen for the Zebrafish C-myb antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish C-myb antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish C-myb antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

    别名

    c-Myb

    背景

    C-Myb is a transcription factor that plays a critical role in the regulation of gene expression during the development and maintenance of hematopoietic stem and progenitor cells. In zebrafish, c-Myb is essential for the formation of definitive blood cells and is widely used as a marker of early hematopoiesis.

    During zebrafish embryogenesis, c-Myb is expressed in the dorsal aorta, where hematopoietic stem cells first emerge, as well as in the developing thymus and other hematopoietic tissues. It regulates the expression of genes involved in cell proliferation, differentiation, and survival. Loss of c-Myb function leads to defects in blood cell development, particularly in the production of lymphoid and myeloid lineages.

    Due to its conserved function in vertebrate hematopoiesis, zebrafish c-Myb is commonly used in research focused on blood development, leukemia, stem cell biology, and gene regulation. Its accessibility in zebrafish models allows for detailed in vivo studies of hematopoietic disorders and drug screening applications.

    UniProt

    F1QP25

    途径

    Chromatin Binding, Positive Regulation of Immune Effector Process
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