ME1 抗体 (AA 1-572)
Our Local Distributor
北京 101111
Quick Overview for ME1 抗体 (AA 1-572) (ABIN7869481)
抗原
See all ME1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-572
-
原理
- ME1 Antibody / Malic enzyme 1
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids M1-Q572) was used as the immunogen for the ME1 antibody.
-
亚型
- IgG
-
-
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibody
ME1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) antibodyKO Validated ME1 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 161-519) antibodyME1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (C-Term) antibodyME1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (N-Term) antibodyME1 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Pig, 绵羊, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 37-70) antibodyME1 适用: 人 WB 宿主: 兔 Polyclonal RB55906 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-300) antibodyME1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 36-85) antibodyME1 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the ME1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the ME1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
-
别名
- ME1
-
背景
-
ME1 (Malic enzyme 1) is a cytosolic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate, producing NADPH in the process. This reaction plays a critical role in cellular metabolism by linking the tricarboxylic acid (TCA) cycle to lipid biosynthesis and antioxidant defense. ME1-derived NADPH is essential for fatty acid and cholesterol synthesis, as well as for maintaining redox balance in cells.
ME1 is expressed in various tissues, with particularly high levels in lipogenic tissues such as liver, adipose tissue, and lactating mammary gland. Its activity is regulated by nutritional and hormonal signals, including carbohydrate intake and insulin, making it a key player in metabolic adaptation. Due to its involvement in energy metabolism and biosynthetic processes, ME1 has been widely studied in the contexts of metabolic regulation and biochemical pathway integration.
The ME1 antibody is a valuable reagent for detecting ME1 in research applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the ME1 antibody from NSJ Bioreagents to assess tissue-specific expression, study its role in lipid metabolism, and investigate its contribution to NADPH production. With strong specificity and reproducible performance, the ME1 antibody supports a wide range of studies in cellular metabolism, enzymology, and biochemical research.
-
UniProt
- P48163
-
途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
-
