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KLC1 抗体 (Light Chain)

The 小鼠 单克隆 anti-KLC1 antibody is suitable to detect KLC1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB.
产品编号 ABIN7869459
发货至: 中国
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Quick Overview for KLC1 抗体 (Light Chain) (ABIN7869459)

抗原

See all KLC1 抗体
KLC1 (Kinesin Light Chain 1 (KLC1))

适用

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人, 大鼠, 小鼠

宿主

  • 59
  • 4
小鼠

克隆类型

  • 49
  • 14
单克隆

标记

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This KLC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

4F2D7
  • 抗原表位

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    • 3
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    • 2
    • 2
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    • 1
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    AA 1-537, Light Chain

    原理

    Kinesin light chain 1 Antibody / KLC1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M1-D537) was used as the immunogen for the Kinesin light chain 1 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the KLC1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the KLC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    KLC1 (Kinesin Light Chain 1 (KLC1))

    别名

    Kinesin light chain 1

    背景

    Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

    UniProt

    Q07866

    途径

    Ribonucleoprotein Complex Subunit Organization
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