KLC1 抗体 (AA 1-537)
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Quick Overview for KLC1 抗体 (AA 1-537) (ABIN7869457)
抗原
See all KLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-537
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原理
- KLC1 Antibody / Kinesin light chain 1
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids M1-D537) was used as the immunogen for the KLC1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the KLC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the KLC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- KLC1 (Kinesin Light Chain 1 (KLC1))
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别名
- KLC1
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背景
- Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.
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UniProt
- Q07866
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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