HDAC3 抗体 (AA 1-428)
Our Local Distributor
北京 101111
Quick Overview for HDAC3 抗体 (AA 1-428) (ABIN7869352)
抗原
See all HDAC3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-428
-
原理
- HDAC3 Antibody
-
纯化方法
- Affinity purified
-
免疫原
- Amino acids M1-I428 from the human protein were used as the immunogen for the HDAC3 antibody.
-
亚型
- IgG
-
-
anti-Histone Deacetylase 3 (HDAC3) (AA 299-428) antibody
HDAC3 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (pSer424) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 411-428), (C-Term) antibodyHDAC3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 319-428) antibodyHDAC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyHDAC3 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibodyHDAC3 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 2F9-4B7 unconjugated
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibodyHDAC3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 3 (HDAC3) antibodyKD Validated HDAC3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB860 unconjugated Recombinant Antibody
-
-
应用备注
- Optimal dilution of the HDAC3 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- Store the HDAC3 antibody at -20oC.
-
-
- HDAC3 (Histone Deacetylase 3 (HDAC3))
-
别名
- HDAC3
-
背景
- HDAC3 (HISTONE DEACETYLASE 3) is a member of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC3 gene. The HDAC3 gene is mapped to 5q31.3. HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. And this gene is regarded as a potential tumor suppressor gene. HDAC3 has an open reading frame of 428 amino acids and shares 53 % amino acid identity with HDAC1 and 52 % with HDAC2. The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2. All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4. HDAC3 recruitment to the genome displays a circadian rhythm in mouse liver.
-
UniProt
- O15379
-
途径
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-
