SNX6 抗体 (AA 1-406)
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Quick Overview for SNX6 抗体 (AA 1-406) (ABIN7869323)
抗原
See all SNX6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-406
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原理
- SNX6 Antibody / Sorting Nexin 6
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids M1-T406 from the human protein were used as the immunogen for the SNX6 antibody.
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亚型
- IgG
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anti-Sorting Nexin 6 (SNX6) (AA 1-406) antibody
SNX6 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 6 (SNX6) (AA 1-290) antibodySNX6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B11 unconjugated
anti-Sorting Nexin 6 (SNX6) (AA 1-290) antibodySNX6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 6 (SNX6) antibodySNX6 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 6 (SNX6) (AA 211-310) antibodySNX6 适用: 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 6 (SNX6) (AA 208-257) antibodySNX6 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SNX6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SNX6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNX6 (Sorting Nexin 6 (SNX6))
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别名
- SNX6
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背景
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SNX6 (Sorting Nexin 6) is a member of the sorting nexin family, a group of proteins that regulate intracellular trafficking and endosomal sorting. It contains a Phox (PX) domain that binds phosphoinositides, allowing SNX6 to associate with membranes of the endosomal system. Through its involvement in vesicular transport, SNX6 helps direct cargo proteins to specific cellular destinations. A SNX6 antibody is widely used in studies of endosomal trafficking, protein sorting, and membrane dynamics.
SNX6 is a component of the retromer complex, which mediates the retrograde transport of proteins from endosomes back to the trans-Golgi network. This pathway is crucial for maintaining receptor recycling, lysosomal enzyme trafficking, and signaling receptor turnover. By studying SNX6 with a SNX6 antibody, researchers can evaluate its role in cargo recognition and retromer function, as well as its contribution to cellular homeostasis.
Beyond vesicle trafficking, SNX6 has been implicated in multiple signaling pathways. It interacts with transforming growth factor beta (TGF-i²) receptors and may influence TGF-i² signaling, thereby linking endosomal sorting to cell growth and differentiation. Dysregulation of SNX6 expression or function has been associated with cancer progression, neurodegeneration, and viral infection. Employing a SNX6 antibody enables scientists to explore these diverse biological roles and to better understand how endosomal dynamics intersect with signaling networks.
NSJ Bioreagents offers a high-quality SNX6 antibody validated for applications including western blot, immunohistochemistry, and immunofluorescence. Choosing a SNX6 antibody from NSJ Bioreagents ensures reliable performance and reproducible results in studies of protein trafficking, retromer biology, and disease-related signaling. -
UniProt
- Q9UNH7
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途径
- EGFR Signaling Pathway
抗原
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