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Phospholamban 抗体 (AA 1-36)

The 兔 多克隆 anti-Phospholamban antibody is suitable to detect Phospholamban in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7869249
发货至: 中国
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Quick Overview for Phospholamban 抗体 (AA 1-36) (ABIN7869249)

抗原

See all Phospholamban (PLN) 抗体
Phospholamban (PLN)

适用

  • 87
  • 25
  • 24
  • 3
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 87
  • 2
  • 1

克隆类型

  • 85
  • 5
多克隆

标记

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  • 6
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  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
This Phospholamban antibody is un-conjugated

应用范围

  • 36
  • 35
  • 26
  • 26
  • 19
  • 11
  • 9
  • 7
  • 7
  • 7
  • 6
  • 5
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 27
    • 17
    • 11
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-36

    原理

    PLB Antibody / Phospholamban / PLN

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M1-C36) was used as the immunogen for the PLB antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PLB antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PLB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Phospholamban (PLN)

    别名

    PLB

    背景

    Phospholamban is a 52 amino acid integral membrane protein that regulates the Ca2+ pump in cardiac muscle and skeletal muscle cells. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. Phospholamban is also expressed in slow-twitch skeletal muscle and some smooth muscle cells. It is observed that human ventricle and quadriceps displayed high levels of phospholamban transcripts and proteins, with markedly lower expression observed in smooth muscles, while the right atrium also expressed low levels of phospholamban. The structure of the human phospholamban gene closely resembles that reported for chicken, rabbit, rat, and mouse. Comparison of the human to other mammalian phospholamban genes indicated a marked conservation of sequence for at least 217 bp upstream of the transcription start site.

    UniProt

    P26678

    途径

    Negative Regulation of Transporter Activity
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