Septin 7 抗体 (AA 1-348)
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Quick Overview for Septin 7 抗体 (AA 1-348) (ABIN7869229)
抗原
See all Septin 7 (SEPT7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-348
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原理
- Zebrafish Septin7 Antibody / Septin7a / Septin7b
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Septin7 recombinant protein (amino acids M1-K348) was used as the immunogen for the Zebrafish Septin7 antibody.
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亚型
- Ig Fraction
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anti-Septin 7 (SEPT7) (AA 1-351) antibody
SEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 387-437) antibodySEPT7 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodyKD Validated SEPT7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4470 unconjugated Recombinant Antibody
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 308-437) antibodySEPT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) antibodySEPT7 适用: 人 WB, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (AA 201-300) antibodySEPT7 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Septin 7 (SEPT7) (C-Term) antibodySEPT7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Septin7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Septin7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Septin 7 (SEPT7)
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别名
- Septin7
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背景
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Zebrafish Septin7 is a member of the septin family of GTP binding proteins that are involved in cytoskeletal organization, membrane dynamics, and cell division. Septins form hetero oligomeric complexes that act as scaffolds and diffusion barriers, contributing to processes such as cytokinesis, vesicle trafficking, and cell polarity. Septin7 plays a crucial structural role in septin filament assembly and is required for proper cell morphology and intracellular transport.
Zebrafish Septin7 is an ortholog of the human SEPTIN7 protein, with strong sequence and functional conservation across species. In zebrafish, Septin7 is encoded by 2 isoforms, Septin7a and Septin7b. Both isoforms share similar functions but may exhibit differences in expression patterns during development or in specific tissues. The presence of Septin7a and Septin7b in zebrafish provides a unique opportunity to study how septin isoforms cooperate or diverge in their roles within the cytoskeleton and signaling pathways.
Septin7 is particularly important during cellular processes that require cytoskeletal remodeling, such as neurite outgrowth, epithelial polarity, and germ cell development. Disruption of Septin7 function can lead to defects in cytokinesis, altered vesicle trafficking, and impaired cell signaling.
Antibodies against zebrafish Septin7 protein are useful for studying the organization of septin filaments and their interactions with actin and microtubule networks. These antibodies are valuable in applications such as western blot, immunohistochemistry, immunofluorescence, and ELISA. The conservation of Septin7 between zebrafish and human systems also makes zebrafish a powerful model for exploring the fundamental roles of SEPTIN7 in cell division, morphogenesis, and disease.
抗原
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