GHITM 抗体 (AA 1-345)
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Quick Overview for GHITM 抗体 (AA 1-345) (ABIN7869226)
抗原
See all GHITM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-345
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原理
- GHITM Antibody / MICS1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-K345) was used as the immunogen for the GHITM antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the GHITM antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GHITM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))
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别名
- GHITM
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背景
- Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 or DERP2, is a mitochondrial protein which localizes in the inner membrane. GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.
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UniProt
- Q9H3K2
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途径
- SARS-CoV-2 Protein Interactome
抗原
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