HSD17B8 抗体 (AA 1-336)
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Quick Overview for HSD17B8 抗体 (AA 1-336) (ABIN7869210)
抗原
See all HSD17B8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-336
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原理
- RING2 Antibody / RNF2 / RING1B
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-K336) was used as the immunogen for the RING2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RING2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RING2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
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别名
- RING2
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背景
- E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
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UniProt
- Q99496
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途径
- Steroid Hormone Biosynthesis
抗原
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