ETV4 抗体 (AA 1-333)
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Quick Overview for ETV4 抗体 (AA 1-333) (ABIN7869205)
抗原
See all ETV4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-333
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原理
- Zebrafish Etv4 Antibody / ETS translocation variant 4 / Pea3
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Etv4 recombinant protein (amino acids M1-E333) was used as the immunogen for the Zebrafish Etv4 antibody.
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亚型
- Ig Fraction
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anti-Ets Variant 4 (ETV4) (AA 1-207) antibody
ETV4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 419-447), (C-Term) antibodyETV4 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20008 unconjugated
anti-Ets Variant 4 (ETV4) (AA 1-207) antibodyETV4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G9-1B9 unconjugated
anti-Ets Variant 4 (ETV4) (AA 181-230) antibodyETV4 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 50-109) antibodyETV4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A2G3 unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (Middle Region) antibodyETV4 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 426-455), (C-Term) antibodyETV4 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (Center) antibodyETV4 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Etv4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Etv4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ETV4 (Ets Variant 4 (ETV4))
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别名
- Etv4
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背景
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Ets variant 4 (Etv4), also known as Pea3, is a member of the ETS family of transcription factors characterized by a conserved ETS DNA-binding domain that recognizes purine-rich sequences in target gene promoters. In zebrafish (Danio rerio), etv4 plays an essential role in embryonic development, particularly in processes regulated by fibroblast growth factor (FGF) signaling.
Etv4 functions as a key downstream effector of FGF signaling pathways, mediating transcriptional responses critical for tissue patterning and organogenesis. During zebrafish embryogenesis, etv4 is expressed in a variety of dynamic domains including the posterior mesoderm, developing somites, neural crest, and the pronephros. It acts in concert with other Pea3 subfamily members such as Etv5 to regulate genes involved in cell migration, proliferation, and differentiation.
Zebrafish etv4 has been extensively studied in the context of limb and fin development, neuromast formation, and branchial arch morphogenesis, making it a useful molecular marker for FGF activity and mesenchymal-epithelial interactions. Disruption of etv4 expression or function impairs normal developmental processes, underscoring its regulatory importance.
Due to its conserved function and regulated expression, zebrafish Etv4 serves as a valuable model for studying ETS transcription factors in vertebrate development and disease pathways, including cancer metastasis and skeletal disorders.
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UniProt
- Q9PUQ1
抗原
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