PRMT1 抗体 (AA 1-311)
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Quick Overview for PRMT1 抗体 (AA 1-311) (ABIN7869179)
抗原
See all PRMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-311
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原理
- HRMT1L2 Antibody / PRMT1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-H311) was used as the immunogen for the HRMT1L2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HRMT1L2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HRMT1L2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))
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别名
- HRMT1L2
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背景
- Protein arginine N-methyltransferase 1, also called Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2 (HRMT1L2) is an enzyme that in humans is encoded by the PRMT1 gene. It is mapped to 19q13.33. This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
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UniProt
- Q99873
抗原
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