DREAM 抗体 (AA 1-30)
Our Local Distributor
北京 101111
Quick Overview for DREAM 抗体 (AA 1-30) (ABIN7869096)
抗原
See all DREAM (KCNIP3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-30
-
原理
- KCNIP3 Antibody / Calsenilin / KChIP3
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the KCNIP3 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the KCNIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the KCNIP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
-
别名
- KCNIP3
-
背景
- KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.
-
UniProt
- Q9Y2W7
抗原
-