HDAC11 抗体 (AA 1-30)
Our Local Distributor
北京 101111
Quick Overview for HDAC11 抗体 (AA 1-30) (ABIN7869091)
抗原
See all HDAC11 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-30
-
原理
- HDAC11 Antibody
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the HDAC11 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the HDAC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the HDAC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- HDAC11 (Histone Deacetylase 11 (HDAC11))
-
别名
- HDAC11
-
背景
- HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
-
UniProt
- Q96DB2
抗原
-