CDK12 抗体 (AA 1-30)
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Quick Overview for CDK12 抗体 (AA 1-30) (ABIN7869083)
抗原
See all CDK12 (CRKRS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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原理
- CrkRS Antibody / CDK12 / Cyclin-dependent kinase 12
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免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this CrkRS antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the CrkRS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CrkRS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
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别名
- CrkRS
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背景
- CrkRS, also known as Cdc2-related kinase, arginine/serine-rich, CDK12 and Cyclin-dependent kinase 12, is a cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. It also regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability.
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UniProt
- Q9NYV4
抗原
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