Prohibitin 2 抗体 (AA 1-299)
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北京 101111
Quick Overview for Prohibitin 2 抗体 (AA 1-299) (ABIN7869078)
抗原
See all Prohibitin 2 (PHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-299
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原理
- PHB2 Antibody / Prohibitin 2
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-K299) was used as the immunogen for the PHB2 antibody.
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亚型
- IgG
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anti-Prohibitin 2 (PHB2) antibody
PHB2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Prohibitin 2 (PHB2) (AA 225-255) antibodyPHB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15576 unconjugated
anti-Prohibitin 2 (PHB2) (C-Term) antibodyPHB2 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 197-226), (C-Term) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10631 unconjugated
anti-Prohibitin 2 (PHB2) (Tyr128) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PHB2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PHB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Prohibitin 2 (PHB2)
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别名
- PHB2
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背景
- PHB2 (Prohibitin 2), also called Repressor of Estrogen Receptor Activity (REA), is a protein that in humans is encoded by the PHB2 gene. The International Radiation Hybrid Mapping Consortium mapped the PHB2 gene to chromosome 12. Montano et al.(1999) showed that REA enhanced the potency of a dominant-negative ER-alpha mutant and antiestrogens as suppressors of ER-alpha activity in Chinese hamster ovary cells. When coexpressed with wildtype ER-alpha or ER-beta(ESR2), REA suppressed activation of a reporter gene in a dose-dependent manner. REA had no effect on reporter activity in the absence of liganded ER, and it had no effect on the transcriptional activities of other hormone receptors. Mutation analysis showed that an N-terminal domain and a central domain of REA were required for its repressor activity.
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UniProt
- Q99623
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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