RASD1 抗体 (AA 1-281)
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Quick Overview for RASD1 抗体 (AA 1-281) (ABIN7869043)
抗原
See all RASD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-281
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原理
- Dexras1 Antibody / RASD1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-S281) was used as the immunogen for the Dexras1 antibody.
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亚型
- IgG
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anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody
RASD1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31294 unconjugated
anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 21-120) antibodyRASD1 适用: 小鼠, 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 1-110) antibodyRASD1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 132-281) antibodyRASD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Dexras1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Dexras1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))
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别名
- Dexras1
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背景
- Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9Y272
抗原
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