HAX1 抗体 (AA 1-279)
Our Local Distributor
北京 101111
Quick Overview for HAX1 抗体 (AA 1-279) (ABIN7869041)
抗原
See all HAX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-279
-
原理
- HAX1 Antibody / HCLS1-associated protein X-1
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids M1-R279) was used as the immunogen for the HAX1 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the HAX1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the HAX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
-
别名
- HAX1
-
背景
- HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- O00165
-
途径
- Regulation of Actin Filament Polymerization
抗原
-