KCNIP2 抗体 (AA 1-270)
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Quick Overview for KCNIP2 抗体 (AA 1-270) (ABIN7869013)
抗原
See all KCNIP2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-270
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原理
- KChIP2 Antibody / KCNIP2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein (within amino acids 1-270) from the human protein was used as the immunogen for the KChIP2 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the KChIP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the KChIP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))
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别名
- KChIP2
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背景
- In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4Alpha-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99 % nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.
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UniProt
- Q9NS61
抗原
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