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RAD17 抗体 (AA 1-267)

This 兔 多克隆 antibody specifically detects RAD17 in WB, ELISA, FACS 和 IHC (p). It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN7869008
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RAD17 抗体 (AA 1-267) (ABIN7869008)

抗原

See all RAD17 抗体
RAD17

适用

  • 113
  • 32
  • 20
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 111
  • 4
  • 3

克隆类型

  • 103
  • 14
多克隆

标记

  • 57
  • 7
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This RAD17 antibody is un-conjugated

应用范围

  • 69
  • 34
  • 26
  • 26
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  • 20
  • 14
  • 13
  • 9
  • 6
  • 4
  • 1
  • 1
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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 21
    • 15
    • 13
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-267

    原理

    Rad17 Antibody

    纯化方法

    Affinity purified

    免疫原

    Recombinant mouse protein (amino acids M1-Q267) was used as the immunogen for the Rad17 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Rad17 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Rad17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    RAD17

    别名

    Rad17

    背景

    The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.

    UniProt

    Q6NXW6
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