Synaptoporin 抗体 (AA 1-265)
Our Local Distributor
北京 101111
Quick Overview for Synaptoporin 抗体 (AA 1-265) (ABIN7869003)
抗原
See all Synaptoporin (SYNPR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-265
-
原理
- SYNPR Antibody / Synaptoporin
-
纯化方法
- Immunogen affinity purified
-
免疫原
- E.coli-derived human Synaptoporin/SYNPR recombinant protein (Position: M1-I265) was used as the immunogen for the SYNPR antibody.
-
亚型
- IgG
-
-
anti-Synaptoporin (SYNPR) (AA 199-265) antibody
SYNPR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (C-Term) antibodySYNPR 适用: 人, 大鼠, 小鼠, Hamster WB, IHC, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 250-265) antibodySYNPR 适用: 大鼠, 小鼠, Hamster WB, IHC, IHC (p), ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 31-130) antibodySYNPR 适用: 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 91-140) antibodySYNPR 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 192-218), (C-Term) antibodySYNPR 适用: 人 WB 宿主: 兔 Polyclonal RB39893 unconjugated
anti-Synaptoporin (SYNPR) (Middle Region) antibodySYNPR 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the SYNPR antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the SYNPR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Synaptoporin (SYNPR)
-
别名
- SYNPR
-
背景
-
SYNPR antibody detects Synaptoporin, encoded by the SYNPR gene. Synaptoporin is a synaptic vesicle protein belonging to the synaptophysin family and is highly enriched in hippocampal mossy fiber terminals. SYNPR antibody provides researchers with a specific reagent to study synaptic vesicle biology, neurotransmission, and neural circuit regulation.
Synaptoporin is a small integral membrane protein that shares structural similarity with synaptophysin but has distinct expression patterns. Research using SYNPR antibody has shown that Synaptoporin localizes to presynaptic vesicles, where it contributes to vesicle cycling and exocytosis. Its enrichment in specific hippocampal circuits highlights its specialized role in regulating excitatory neurotransmission.
Studies with SYNPR antibody have revealed that Synaptoporin is particularly abundant in mossy fiber terminals of granule cells projecting to CA3 pyramidal neurons. This selective localization has made SYNPR a useful marker for hippocampal circuitry studies. Its presence supports efficient vesicle recycling, ensuring sustained neurotransmitter release during high-frequency stimulation.
Synaptoporin has also been implicated in synaptic plasticity. Research using SYNPR antibody has demonstrated that altered expression or distribution of Synaptoporin correlates with changes in long-term potentiation and synaptic remodeling. This suggests that Synaptoporin contributes to the molecular basis of learning and memory by supporting plastic synaptic responses.
Dysregulation of Synaptoporin is associated with neurological disease. Studies with SYNPR antibody have linked altered expression to epilepsy and neurodegenerative disorders, where synaptic dysfunction is a hallmark. These associations emphasize the relevance of SYNPR to both basic neuroscience and pathology.
SYNPR antibody is widely used in immunohistochemistry, immunofluorescence, and western blotting. Immunohistochemistry highlights localization in hippocampal circuits, immunofluorescence reveals colocalization with synaptic vesicle markers, and western blotting quantifies protein levels in neuronal tissue. These applications make SYNPR antibody indispensable for neuroscience research.
By supplying validated SYNPR antibody reagents, NSJ Bioreagents supports studies into synaptic vesicle biology, hippocampal circuitry, and neurological disease. Detection of Synaptoporin provides researchers with insight into how specialized synaptic proteins regulate neurotransmission and plasticity. -
UniProt
- Q8TBG9
抗原
-
