YWHAE 抗体 (AA 1-255)
Our Local Distributor
北京 101111
Quick Overview for YWHAE 抗体 (AA 1-255) (ABIN7868984)
抗原
See all YWHAE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-255
-
原理
- 14-3-3 epsilon Antibody / YWHAE
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant human protein (amino acids M1-Q255) was used as the immunogen for the 14-3-3 epsilon antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the 14-3-3 epsilon antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the 14-3-3 epsilon antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- YWHAE (14-3-3 epsilon (YWHAE))
-
别名
- 14-3-3 epsilon
-
背景
- 14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
-
UniProt
- P62258
-
途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
-