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HMMR 抗体 (AA 1-250)

The 小鼠 单克隆 anti-HMMR antibody (Clone HMMR-8021) (ABIN7868944) specifically detects HMMR in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868944
发货至: 中国
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Quick Overview for HMMR 抗体 (AA 1-250) (ABIN7868944)

抗原

See all HMMR 抗体
HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))

适用

  • 90
  • 43
  • 26
  • 1

宿主

  • 85
  • 5
小鼠

克隆类型

  • 70
  • 20
单克隆

标记

  • 39
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HMMR antibody is un-conjugated

应用范围

  • 67
  • 37
  • 33
  • 27
  • 14
  • 13
  • 13
  • 12
  • 10
  • 4
  • 3
  • 2
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

HMMR-8021
  • 抗原表位

    • 16
    • 15
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-250

    原理

    CD168 Antibody / HMMR

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-250) from the human protein was used as the immunogen for the CD168 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CD168 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CD168 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))

    别名

    CD168

    背景

    Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan that regulates cell adhesion and migration. HA effects are mediated through two receptors, CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM, also designated intracellular hyaluronic acid binding protein (IHABP) and CD168, is a matrix receptor, which is linked to the plasma membrane by a GPI anchor and regulates cell motility. RHAMM expression is upregulated in malignant lymphoid tissues and is subsequently implicated in tumor progression and metastasis formation, as well as signal transduction. Although still unclear, RHAMM is thought to exist as several isoforms ranging in size. A variant isoform, designated v4, is a protein that when over-expressed, is thought to be the cause of transformation and metastasis formation in fibroblasts.

    UniProt

    O75330

    途径

    Glycosaminoglycan Metabolic Process
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