ALAS1 抗体 (AA 1-244)
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Quick Overview for ALAS1 抗体 (AA 1-244) (ABIN7868914)
抗原
See all ALAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-244
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原理
- ALAS1 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-Q244) was used as the immunogen for the ALAS1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ALAS1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ALAS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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别名
- ALAS1
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背景
- This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P13196
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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