NAT15 抗体 (AA 1-242)
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北京 101111
Quick Overview for NAT15 抗体 (AA 1-242) (ABIN7868910)
抗原
See all NAT15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-242
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原理
- NAA60 Antibody / N-alpha-acetyltransferase 60
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human NAA60 recombinant protein (Position: M1-M242) was used as the immunogen for the NAA60 antibody.
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亚型
- IgG
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anti-N-Acetyltransferase 15 (NAT15) (AA 1-242) antibody
NAT15 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) antibodyNAT15 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) (AA 1-100) antibodyNAT15 适用: 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) (AA 1-242) antibodyNAT15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) (AA 1-94) antibodyNAT15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) (C-Term) antibodyNAT15 适用: 人, 山羊, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acetyltransferase 15 (NAT15) (AA 133-160) antibodyNAT15 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB38311 unconjugated
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应用备注
- Optimal dilution of the NAA60 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NAA60 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NAT15 (N-Acetyltransferase 15 (NAT15))
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别名
- NAA60
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背景
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NAA60 antibody detects N-alpha-acetyltransferase 60, a Golgi-associated enzyme responsible for acetylating the N-termini of transmembrane and cytosolic proteins. The UniProt recommended name is N-alpha-acetyltransferase 60 (NAA60). This enzyme belongs to the GNAT (GCN5-related N-acetyltransferase) family and contributes to post-translational protein modification, stability, and membrane targeting.
Functionally, NAA60 antibody identifies a 242-amino-acid acetyltransferase localized to the cytosolic face of the Golgi apparatus. NAA60 catalyzes the transfer of an acetyl group from acetyl-CoA to protein N-termini, particularly targeting lysine residues within membrane-bound substrates. Its unique subcellular localization distinguishes it from other N-terminal acetyltransferases (NATs) acting in the cytosol or nucleus.
The NAA60 gene is located on chromosome 16p13.3 and is broadly expressed in mammalian tissues, with enrichment in epithelial and secretory cells. By modifying transmembrane proteins, NAA60 influences vesicle trafficking, protein sorting, and Golgi membrane organization. It also contributes to cell cycle progression and mitotic spindle stability.
Pathologically, altered NAA60 activity has been linked to cell proliferation abnormalities and tumorigenesis. Reduced NAA60 expression affects Golgi morphology and disrupts intracellular transport. Research using NAA60 antibody supports studies in protein acetylation, Golgi biology, and membrane-associated protein regulation.
NAA60 antibody is validated for western blotting, immunohistochemistry, and immunofluorescence to detect acetyltransferases in cell lysates and subcellular fractions. NSJ Bioreagents provides NAA60 antibody reagents optimized for research in protein modification, trafficking, and cell signaling.
Structurally, N-alpha-acetyltransferase 60 contains a conserved acetyl-CoA-binding motif and catalytic residues typical of GNAT enzymes. This antibody enables investigation of NAA60's functional role in post-translational regulation and Golgi-associated protein processing. -
UniProt
- Q9H7X0
抗原
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