Recombinant ACTH 抗体 (AA 1-24)
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Quick Overview for Recombinant ACTH 抗体 (AA 1-24) (ABIN7868897)
抗原
See all ACTH 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-24
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原理
- Recombinant ACTH Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1-24 of human ACTH was used as the immunogen for the recombinant ACTH antibody.
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亚型
- IgG2a, kappa
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应用备注
- Optimal dilution of the recombinant ACTH antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ACTH (Adrenocorticotropic hormone (ACTH))
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别名
- ACTH
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背景
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
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UniProt
- P01189
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
抗原
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