RGS18 抗体 (AA 1-230)
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Quick Overview for RGS18 抗体 (AA 1-230) (ABIN7868879)
抗原
See all RGS18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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原理
- RGS18 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-D230) was used as the immunogen for the RGS18 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RGS18 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RGS18 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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别名
- RGS18
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背景
- Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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UniProt
- Q9NS28
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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