PCMT1 抗体 (AA 1-227)
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Quick Overview for PCMT1 抗体 (AA 1-227) (ABIN7868871)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-227
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原理
- PCMT1 Antibody / Protein-L-isoaspartate(D-aspartate) O-methyltransferase
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids M1-K227) was used as the immunogen for the PCMT1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PCMT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PCMT1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- PCMT1
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背景
- Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- P22061
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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