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CDK5 抗体 (AA 1-226)

The 兔 多克隆 anti-CDK5 antibody (ABIN7868863) specifically detects CDK5 in WB. The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7868863
发货至: 中国
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Quick Overview for CDK5 抗体 (AA 1-226) (ABIN7868863)

抗原

See all CDK5 抗体
CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This CDK5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-226

    原理

    Zebrafish Cdk5 Antibody

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Cdk5 recombinant protein (amino acids M1-Q226) was used as the immunogen for the Zebrafish Cdk5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Cdk5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Cdk5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

    别名

    Cdk5

    背景

    CDK5, Cyclin-Dependent Kinase 5, is also known as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

    UniProt

    Q9DE44

    途径

    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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