SOD2 抗体 (AA 1-224)
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Quick Overview for SOD2 抗体 (AA 1-224) (ABIN7868858)
抗原
See all SOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-224
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原理
- Zebrafish Sod2 Antibody / Superoxide dismutase 2
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Sod2 recombinant protein (amino acids M1-K224) was used as the immunogen for the Zebrafish Sod2 antibody.
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亚型
- Ig Fraction
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anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibody
SOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8H3D2 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8H3F9 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 192-222), (C-Term) antibodySOD2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 41-78) antibodySOD2 适用: 人, 小鼠, Pig, 绵羊 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (PE)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (Atto 390)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (Atto 488)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (FITC)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal dilution of the Zebrafish Sod2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Sod2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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别名
- Sod2
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背景
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Zebrafish Sod2, also known as superoxide dismutase 2, is a manganese containing antioxidant enzyme located in the mitochondrial matrix. It catalyzes the dismutation of superoxide radicals into hydrogen peroxide and oxygen, which is a critical step in defending cells against oxidative stress generated during mitochondrial respiration. Sod2 is essential for maintaining mitochondrial integrity, reducing oxidative damage to proteins, lipids, and DNA, and ensuring proper cellular metabolism and survival.
Zebrafish Sod2 is an ortholog of the human SOD2 protein, with strong sequence and functional conservation. As in humans, Sod2 in zebrafish plays a vital role in protecting highly metabolic tissues such as the brain, heart, and muscles from oxidative damage. Mutations or reduced activity of Sod2 can lead to mitochondrial dysfunction and oxidative stress, contributing to developmental abnormalities and degenerative diseases.
Currently, there are no confirmed isoforms of zebrafish Sod2. It is broadly expressed across tissues but is particularly abundant in cells with high energy demands. Zebrafish models deficient in Sod2 have been used to investigate the consequences of oxidative imbalance and to explore therapeutic approaches aimed at reducing mitochondrial stress.
Antibodies targeting zebrafish Sod2 protein are important tools for studying mitochondrial antioxidant defense systems, oxidative signaling pathways, and stress responses. These antibodies can be utilized in western blot, immunohistochemistry, immunofluorescence, and ELISA to monitor Sod2 levels and localization in zebrafish tissues.
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UniProt
- Q6P980
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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