P5CS 抗体 (AA 1-224)
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Quick Overview for P5CS 抗体 (AA 1-224) (ABIN7868855)
抗原
See all P5CS (ALDH18A1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-224
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原理
- ALDH18A1 Antibody / P5CS
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-A224) was used as the immunogen for the ALDH18A1 antibody.
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亚型
- IgG
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anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibody
ALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 176-205) antibodyALDH18A1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21608 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 575-625) antibodyALDH18A1 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibodyALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-795) antibodyALDH18A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 745-795) antibodyALDH18A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-240) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 35-84) antibodyALDH18A1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (N-Term) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ALDH18A1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ALDH18A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
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别名
- ALDH18A1
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背景
- Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
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UniProt
- P54886
抗原
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