CKAP5 抗体 (AA 1-221)
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Quick Overview for CKAP5 抗体 (AA 1-221) (ABIN7868848)
抗原
See all CKAP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-221
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原理
- CKAP5 Antibody / Ch-TOG
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids M1-L221) was used as the immunogen for the CKAP5 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the CKAP5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CKAP5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))
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别名
- CKAP5
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背景
- Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is mapped to 11p11.2. This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interact ernatively spliced transcript variants encoding different isoforms have been identified.
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UniProt
- Q14008
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途径
- M Phase
抗原
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