TREM2 抗体 (AA 1-200)
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北京 101111
Quick Overview for TREM2 抗体 (AA 1-200) (ABIN7868778)
抗原
See all TREM2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- TREM2 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1-200 was used as the immunogen for the TREM2 antibody.
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亚型
- IgG2b, kappa
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anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-100) antibody
TREM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-228) antibodyTREM2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 22-48), (N-Term) antibodyTREM2 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB38661 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) antibodyTREM2 适用: 人 ELISA, FACS, Func, SPR, BLI 宿主: Human Monoclonal PY314 unconjugated Recombinant Antibody
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (Internal Region) antibodyVerified TREM2 适用: 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-227) antibodyTREM2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) antibody (PE)TREM2 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 78-18 PE
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (C-Term) antibodyTREM2 适用: 小鼠, 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) antibodyTREM2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-161) antibodyTREM2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B5 unconjugated
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应用备注
- Optimal dilution of the TREM2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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注意事项
- Avoid repeated freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Aliquot the TREM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
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别名
- TREM2
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背景
- Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), known as Nasu-Hakola disease , is a recessively inherited disease where individuals display early-onset progressive dementia and bone cysts, which leads to death. Mutations in TYROBP (DAP12), which codes for a membrane receptor component in natural-killer and myeloid cells and mutations in triggering receptor expressed on myeloid cells-2 (TREM-2), correlate well to the pathology of PLOSL. TREM-2 is a cell surface receptor on human monocyte-derived dendritic cells that forms a receptor signaling complex with DAP12 and triggers activation of the immune response in macrophages and dendritic cells (DC). The TREM-2/DAP12 complex is a molecular promoter of upregulation of CC chemokine receptor 7, partial DC maturation, and DC survival through activation of protein tyrosine kinases and extracellular signal regulated kinase. The human chronic inflammatory TREM-2 gene maps to chromosome 6p21.1 and encodes a 230 amino acid protein.
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UniProt
- Q9NZC2
抗原
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