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PON1 抗体 (AA 1-200)

The 小鼠 单克隆 anti-PON1 antibody is suitable to detect PON1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7868700
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PON1 抗体 (AA 1-200) (ABIN7868700)

抗原

See all PON1 抗体
PON1 (Paraoxonase 1 (PON1))

适用

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宿主

  • 106
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  • 1
小鼠

克隆类型

  • 86
  • 39
单克隆

标记

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This PON1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PON1-1351
  • 抗原表位

    • 15
    • 9
    • 7
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    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    Paraoxonase 1 Antibody / PON1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Paraoxonase 1 antibody.

    亚型

    IgG2, kappa
  • 应用备注

    Optimal dilution of the Paraoxonase 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Paraoxonase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PON1 (Paraoxonase 1 (PON1))

    别名

    Paraoxonase 1

    背景

    Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

    UniProt

    P27169
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