PAX4 抗体 (AA 1-200)
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Quick Overview for PAX4 抗体 (AA 1-200) (ABIN7868696)
抗原
See all PAX4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- PAX4 Antibody / Paired box 4 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the PAX4 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the PAX4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the PAX4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PAX4 (Paired Box 4 (PAX4))
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别名
- PAX4
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背景
- Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet beta cell lines MIN6, beta TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.
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UniProt
- O43316
抗原
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