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PAX4 抗体 (AA 1-200)

This 小鼠 单克隆 antibody specifically detects PAX4 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868696
发货至: 中国
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Quick Overview for PAX4 抗体 (AA 1-200) (ABIN7868696)

抗原

See all PAX4 抗体
PAX4 (Paired Box 4 (PAX4))

适用

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  • 16
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  • 1
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宿主

  • 24
  • 18
  • 1
小鼠

克隆类型

  • 26
  • 17
单克隆

标记

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  • 1
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This PAX4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PAX4-7598
  • 抗原表位

    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    PAX4 Antibody / Paired box 4 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the PAX4 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the PAX4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the PAX4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAX4 (Paired Box 4 (PAX4))

    别名

    PAX4

    背景

    Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet beta cell lines MIN6, beta TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.

    UniProt

    O43316
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