Neurogenin 3 抗体 (AA 1-200)
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北京 101111
Quick Overview for Neurogenin 3 抗体 (AA 1-200) (ABIN7868673)
抗原
See all Neurogenin 3 (NEUROG3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- NEUROG3 Antibody / Neurogenin 3 / NGN3
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein (within amino acids 1-200) from the human protein was used as the immunogen for the NEUROG3 antibody.
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亚型
- IgG1, kappa
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anti-Neurogenin 3 (NEUROG3) (AA 40-69), (N-Term) antibody
NEUROG3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02913 unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 1-101) antibodyNEUROG3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 1-101) antibodyNEUROG3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 4B7 unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 1-83) antibodyNEUROG3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 61-160) antibodyNEUROG3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 3 (NEUROG3) antibodyNEUROG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 3 (NEUROG3) (N-Term) antibodyNEUROG3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenin 3 (NEUROG3) antibodyNEUROG3 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 1-214) antibodyNEUROG3 适用: 人 WB 宿主: 小鼠 Monoclonal 1800CT113-128-46 unconjugated
anti-Neurogenin 3 (NEUROG3) (AA 93-214) antibodyNEUROG3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NEUROG3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NEUROG3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Neurogenin 3 (NEUROG3)
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别名
- NEUROG3
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背景
- This antigen is a transcription factor that interacts with NKX2-2 to regulation transcription of NEUROD1. The neurogenin family of proteins belongs to the basic helix-loop-helix (bHLH) superfamily and consists of Neurogenin 1, Neurogenin 2 and Neurogenin 3 (also designated ngn3). bHLH members are transcriptional regulators that determine cell fate. Neurogenin 3 is expressed in discrete regions of developing neurons and in the embryonic pancreatic islets of Langerhans. HNF-6 (hepatocyte nuclear factor 6) acts as a positive regulator of Neurogenin 3 by binding to and stimulating the neurogenin gene promoter. Neurogenin 3 is involved in the initial differentiation of the four islets cell types, while a network of transcription factors, including Hlxb9, Isl1, NeuroD, Nkx-2.2, Nkx-6.4, Pax-4, Pax-6, PDX-1 and Mash1, are required for final differentiation. Neurogenin 3 acts upstream of NeuroD in a bHLH cascade. Neurogenin 3 activates the expression of NeuroD at the onset of islet cell differentiation through box sequences E1 and E3 in the NeuroD promoter.
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UniProt
- Q9Y4Z2
抗原
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