IL22RA2 抗体 (AA 1-200)
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北京 101111
Quick Overview for IL22RA2 抗体 (AA 1-200) (ABIN7868589)
抗原
See all IL22RA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- IL22RA2 Antibody / Interleukin-22 receptor subunit alpha 2
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL22RA2 antibody.
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亚型
- IgG2, kappa
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anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 31-223) antibody
IL22RA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 30-228) antibodyIL22RA2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 165-263) antibodyIL22RA2 适用: 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-231) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 22-263) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) antibodyIL22RA2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (Internal Region) antibodyIL22RA2 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) antibodyIL22RA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) (AA 15-42), (N-Term) antibodyIL22RA2 适用: 人 WB 宿主: 兔 Polyclonal RB38824 unconjugated
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应用备注
- Optimal dilution of the IL22RA2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL22RA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))
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别名
- IL22RA2
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背景
- IL-22RAlpha2 (Interleukin-22 receptor Alpha2 chain), also known as IL-22 binding protein (IL-22BP), cytokine receptor family class II member 10 (CRF2-10) or CRF2- soluble 1 (CRF2-S1), is a soluble, nonsignaling single chain receptor for IL-22. It is highly expressed in intestine and lymph nodes and is also found in spleen, kidney and liver. IL-22RAlpha2 has a cytokine-binding domain that contains two FnIII domains. Its affinity for IL-22 is 4- to 10-fold higher than that of the membrane-bound IL-22 receptor, however it has a dissociation rate up to 20 times lower. By binding to IL-22, IL-22RAlpha2 prevents the binding to the IL-22 membrane-bound receptor and therefore inhibits IL-22 signaling. This suggests that IL-22RAlpha2 may be important in regulating inflammatory responses. In addition, IL-22RAlpha2 can be induced by lipopolysaccharides (LPSs).
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UniProt
- Q969J5
抗原
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