IL18R1 抗体 (AA 1-200)
Our Local Distributor
北京 101111
Quick Overview for IL18R1 抗体 (AA 1-200) (ABIN7868582)
抗原
See all IL18R1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 1-200
-
原理
- IL18R1 Antibody / Interleukin 18 receptor alpha (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL18R1 antibody.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal dilution of the IL18R1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the IL18R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
-
别名
- IL18R1
-
背景
- Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1Alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18RAlpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain.
-
UniProt
- Q13478
抗原
-