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IL18R1 抗体 (AA 1-200)

The 小鼠 单克隆 anti-IL18R1 antibody is suitable to detect IL18R1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7868580
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for IL18R1 抗体 (AA 1-200) (ABIN7868580)

抗原

See all IL18R1 抗体
IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL18R1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

IL18R1-7592
  • 抗原表位

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    AA 1-200

    原理

    Interleukin 18 receptor alpha Antibody / IL18R1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Interleukin 18 receptor alpha antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Interleukin 18 receptor alpha antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Interleukin 18 receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

    别名

    Interleukin 18 receptor alpha

    背景

    Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18Ralpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain.

    UniProt

    Q13478
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