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Recombinant CNN1 抗体 (AA 1-200)

The 小鼠 单克隆 anti-CNN1 antibody (Clone rCNN1-9164) (ABIN7868395) specifically detects CNN1 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868395
发货至: 中国
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Quick Overview for Recombinant CNN1 抗体 (AA 1-200) (ABIN7868395)

抗原

See all CNN1 抗体
CNN1 (Calponin 1 (CNN1))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CNN1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RCNN1-9164
  • 抗原表位

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    AA 1-200

    原理

    Recombinant CNN1 Antibody / Calponin-1

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 1-200) of human CNN1 protein was used as the immunogen for the recombinant CNN1 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the recombinant CNN1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant CNN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CNN1 (Calponin 1 (CNN1))

    别名

    CNN1

    背景

    Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

    UniProt

    P51911
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