SPAG7 抗体 (AA 1-199)
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Quick Overview for SPAG7 抗体 (AA 1-199) (ABIN7868361)
抗原
See all SPAG7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-199
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原理
- SPAG7 Antibody / Sperm-associated antigen 7
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids M1-D199 from the human protein were used as the immunogen for the SPAG7 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SPAG7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SPAG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SPAG7 (Sperm Associated Antigen 7 (SPAG7))
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别名
- SPAG7
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背景
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SPAG7 (Sperm-associated antigen 7) is a cytoplasmic RNA-binding protein that plays a role in RNA processing and transport. While initially identified in the context of reproductive biology, SPAG7 is expressed in a range of tissues and is thought to participate in the regulation of RNA metabolism, including splicing and ribonucleoprotein complex formation. A SPAG7 antibody is frequently used in studies of RNA regulation, germ cell biology, and post-transcriptional gene control.
SPAG7 is localized to the cytoplasm and has been associated with RNA-binding activity that influences the stability and localization of specific transcripts. This suggests an important role in coordinating gene expression at the post-transcriptional level. Employing a SPAG7 antibody enables researchers to examine its subcellular distribution and assess its contribution to RNA-based regulatory pathways.
Although initially discovered in sperm, SPAG7 has broader biological functions beyond reproductive processes. It has been reported to interact with nuclear pore and ribonucleoprotein-associated proteins, supporting its involvement in RNA export and turnover. Altered SPAG7 expression patterns have been observed in certain pathological contexts, including cancer, where RNA regulation is frequently disrupted. Using a SPAG7 antibody provides a valuable tool to explore these potential disease associations and clarify its functional significance.
NSJ Bioreagents offers a high-quality SPAG7 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Choosing a SPAG7 antibody from NSJ Bioreagents ensures consistent performance and reliable detection in studies of RNA processing, germ cell function, and molecular regulation. -
UniProt
- O75391
抗原
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