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SPAG7 抗体 (AA 1-199)

The 兔 多克隆 anti-SPAG7 antibody is suitable to detect SPAG7 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, FACS, IF 和 IHC (p).
产品编号 ABIN7868361
发货至: 中国
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Quick Overview for SPAG7 抗体 (AA 1-199) (ABIN7868361)

抗原

See all SPAG7 抗体
SPAG7 (Sperm Associated Antigen 7 (SPAG7))

适用

  • 7
  • 5
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  • 3
  • 3
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  • 2
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人, 大鼠, 小鼠

宿主

  • 7

克隆类型

  • 7
多克隆

标记

  • 7
This SPAG7 antibody is un-conjugated

应用范围

  • 7
  • 3
  • 3
  • 1
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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 3
    • 1
    • 1
    AA 1-199

    原理

    SPAG7 Antibody / Sperm-associated antigen 7

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids M1-D199 from the human protein were used as the immunogen for the SPAG7 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SPAG7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the SPAG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    SPAG7 (Sperm Associated Antigen 7 (SPAG7))

    别名

    SPAG7

    背景

    SPAG7 (Sperm-associated antigen 7) is a cytoplasmic RNA-binding protein that plays a role in RNA processing and transport. While initially identified in the context of reproductive biology, SPAG7 is expressed in a range of tissues and is thought to participate in the regulation of RNA metabolism, including splicing and ribonucleoprotein complex formation. A SPAG7 antibody is frequently used in studies of RNA regulation, germ cell biology, and post-transcriptional gene control.

    SPAG7 is localized to the cytoplasm and has been associated with RNA-binding activity that influences the stability and localization of specific transcripts. This suggests an important role in coordinating gene expression at the post-transcriptional level. Employing a SPAG7 antibody enables researchers to examine its subcellular distribution and assess its contribution to RNA-based regulatory pathways.

    Although initially discovered in sperm, SPAG7 has broader biological functions beyond reproductive processes. It has been reported to interact with nuclear pore and ribonucleoprotein-associated proteins, supporting its involvement in RNA export and turnover. Altered SPAG7 expression patterns have been observed in certain pathological contexts, including cancer, where RNA regulation is frequently disrupted. Using a SPAG7 antibody provides a valuable tool to explore these potential disease associations and clarify its functional significance.

    NSJ Bioreagents offers a high-quality SPAG7 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Choosing a SPAG7 antibody from NSJ Bioreagents ensures consistent performance and reliable detection in studies of RNA processing, germ cell function, and molecular regulation.

    UniProt

    O75391
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