HSPB8 抗体 (AA 1-196)
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Quick Overview for HSPB8 抗体 (AA 1-196) (ABIN7868355)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-196
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原理
- HSP22 Antibody / HSPB8
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-T196) was used as the immunogen for the Hsp22 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Hsp22 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Hsp22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSP22
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背景
- Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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UniProt
- Q9UJY1
抗原
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