VPRBP 抗体 (AA 1-195)
The 兔 多克隆 anti-VPRBP antibody (ABIN7868350) specifically detects VPRBP in ELISA, WB, FACS, IF 和 IHC (p).
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7868350
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for VPRBP 抗体 (AA 1-195) (ABIN7868350)
抗原
See all VPRBP 抗体
VPRBP
(Vpr (HIV-1) Binding Protein (VPRBP))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This VPRBP antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
-
-
抗原表位
- AA 1-195
-
原理
- VPRBP Antibody / DCAF1
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids M1-R195) was used as the immunogen for the VPRBP antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the VPRBP antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the VPRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- VPRBP (Vpr (HIV-1) Binding Protein (VPRBP))
-
别名
- VPRBP
-
物质类
- Viral Protein
-
背景
- VprBP was first identified as a protein that can interact with HIV-1 viral protein R. It is a component of the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex that could interact with HIV-1 virus Vpr protein and HIV-2 virus Vpx protein. VprBP is a 1,507-amino acid protein that contains conserved domains, including YXXY repeats, the Lis homology motif, and WD40 repeats. Through binding to Vpr, VprBP allows Vpr to modulate the catalytic activity of the CUL4-DDB1 complex, which in turn leads to the induction of G2 phase arrest in the virus-infected cells. Recently it has been reported that VprBP is able to regulate the p53-induced transcription and apoptotic pathway.
-
UniProt
- Q9Y4B6
抗原
-
You are here:
