ITPA 抗体 (AA 1-194)
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Quick Overview for ITPA 抗体 (AA 1-194) (ABIN7868347)
抗原
See all ITPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-194
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原理
- ITPA Antibody / Inosine triphosphate pyrophosphatase / ITPase
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids M1-A194) was used as the immunogen for the ITPA antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ITPA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ITPA Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ITPA (Inosine Triphosphatase (ITPA))
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别名
- ITPA
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背景
- Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae, the protein is also encoded by some RNA viruses of the Potyviridae family. This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
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UniProt
- Q9BY32
抗原
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