CBX5 抗体 (AA 1-191)
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Quick Overview for CBX5 抗体 (AA 1-191) (ABIN7868333)
抗原
See all CBX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-191
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原理
- HP1 alpha Antibody / CBX5
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-S191) was used as the immunogen for the HP1 alpha antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HP1 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HP1 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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别名
- HP1 alpha
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背景
- This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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UniProt
- P45973
抗原
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