Centrin 1 抗体 (AA 1-172)
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Quick Overview for Centrin 1 抗体 (AA 1-172) (ABIN7868248)
抗原
See all Centrin 1 (CETN1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-172
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原理
- Centrin 1 Antibody / CETN1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the Centrin 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Centrin 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Centrin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))
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别名
- Centrin 1
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背景
- EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
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UniProt
- Q12798
抗原
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