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Centrin 1 抗体 (AA 1-172)

This 小鼠 单克隆 antibody specifically detects Centrin 1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868246
发货至: 中国
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Quick Overview for Centrin 1 抗体 (AA 1-172) (ABIN7868246)

抗原

See all Centrin 1 (CETN1) 抗体
Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

适用

  • 30
  • 19
  • 2

宿主

  • 25
  • 20
小鼠

克隆类型

  • 27
  • 18
单克隆

标记

  • 31
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Centrin 1 antibody is un-conjugated

应用范围

  • 34
  • 13
  • 13
  • 12
  • 10
  • 9
  • 4
  • 3
  • 3
  • 3
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CETN1-9877
  • 抗原表位

    • 19
    • 15
    • 2
    • 1
    • 1
    • 1
    AA 1-172

    原理

    CEN1 Antibody / Centrin 1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the CEN1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CEN1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CEN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

    别名

    CEN1

    背景

    EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

    UniProt

    Q12798
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