NLRP7 抗体 (AA 1-169)
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Quick Overview for NLRP7 抗体 (AA 1-169) (ABIN7868239)
抗原
See all NLRP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-169
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原理
- NLRP7 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-L169) was used as the immunogen for the NLRP7 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NLRP7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NLRP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))
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别名
- NLRP7
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背景
- NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- Q8WX94
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途径
- Inflammasome
抗原
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